The Genomic Diet (ebook on line in English)

Inflammation, what is it?



The Genomic Diet: 11st chapter  Inflammation, what is it?

Inflammation is:

Rubor = Redness (Blood)
Tumor = Swelling (Edema swelling)
Calor = Heat (Temperature rise)
Dolor = Pain (Alteration of biochemical functions to the local level)
Function Lesa = Functionality (Reduction or loss of function)

Rubor, Tumor, Calor, Dolor and Function Lesa” are the terms that cause inflammation.

The first manifestation of illness are inflammations, are a defense mechanism wherein the goal of the body is to localize the causative agent. Even in this case, the human body defends itself.

The inflammations destroys and dilutes harmful agents and, at the same time, repairs and rebuilds damaged tissue.
Inflammation can be acute, chronic, or granulomatous. Acute is an immediate response to an offendingagent. It becomes chronic when it persists. Granulomatous diseases manifest themselves in a type of immune response.

The causes are numerous: from the simple shock of an elbow against the wall, to pathogens, to organic changes or predisposition due to conditions such as uric acid toxicity (gout). In granulomatous inflammations, there are many cases of hepatitis and Crohn’s disease.

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Food allergies, intolerances, and bio unavailability can help increase the number of outbreaks of acute and chronic inflammations.

These outbreaks can also be deposits of toxins of bacterial, viral and environmental causes.

The neurokinin NGF

The neurokinin NGF (Nerve Growth Factor), discovered by Nobel Prize winner Rita Levi Montalcini, when issued, increases the cells that cause inflammations: mast cells.

NGF has been found not only in nervous tissue but in patients with bronchial asthma in the respiratory tract (European Respiratory Journal).In the event of a traumatic event, our body releases NGF.

Allergies and inflammations occur in tandem.

Macrophages accumulate in the fatty tissue to clean up dead cells which also causes inflammation.

Adiponectin, an anti-inflammatory substance, could be one of the protective factors for vascular disease especially in the case of diabetes II where the vascular complication is very important.

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A decrease of “adiponectin,” a protein messenger group of adipokines (leptin, resistin, adiponectin, visfatin), gives important signals to the mechanisms of inflammation.

Low levels of this protein can be found in cardiovascular diseases such as myocardial infarction, obesity, and in insulin resistance of type II diabetics.

The worsening of inflammation leads to clot formations which is good for cell regeneration but also predisposes a person to heart attacks and strokes.

With weight loss, obesity can fetch a good level of adiponectin. According to a study by the University of California at San Diego published in the journal “CELL,” mild inflammation is normal for the development of the immune system, but the chronic inflammation disrupts the balance and leads to cancer with an increase of P100 protein.


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